miR-100 induces epithelial-mesenchymal transition but suppresses tumorigenesis, migration and invasion.
Whether epithelial-mesenchymal VIT A W E OIL transition (EMT) is always linked to increased tumorigenicity is controversial.Through microRNA (miRNA) expression profiling of mammary epithelial cells overexpressing Twist, Snail or ZEB1, we identified miR-100 as a novel EMT inducer.Surprisingly, miR-100 inhibits the tumorigenicity, motility and invasi